Research focus 3: Bacteria - Host interactions

RIL-seq analysis revealed a new class of sRNAs, four UTR-derived sRNAs whose expression is controlled by the flagella sigma factor (σF). These sRNAs are conserved among pathogenic species and we decipher the mode of action of the σF-dependent sRNAs and uncover their effect on flagella synthesis, bacterial physiology and pathogenicity.

Swarming of two E. coli strains on a low concentration agar plate, one emits a red fluorescence signal and the other one emits a green fluorescence signal.